After working with tires as a part time job for 9+ years, I don't recomend it. It tends to cause metal wheels to rust and aluminum/mag wheels to corrode. It also can change the rubber composition to the point that patches just fall off no matter what you try. That means you have to tube it or replace it. If you ever do have to use it, have the tire repaired ASAP. The tire and wheel need to be rinsed with hot water to help cut the chemicals.
As far as the ride and miles, I agree with the rest. Don't push it. When I traded in my 89 for my 07, we rode 425 miles to get it on Sat. and rode home on Sun. (1 year ago April 28th) That was about the perfect ride. I have done 750 miles from Spearfish, SD to Manhattan, KS a couple of times. This was for Sturgis, bike week. Usually hotter in August as we all know. That was done only so I could get back for work. I don't recomend it at all if you can avoid it. Also for the hotter weather, last year going through Texas, Louisiana, Missippi, etc. we found the bandana around the neck and pouring water on it sure helps keep you cool!
Overall, just enjoy the ride and be safe!!